A Bacteriological profile and Antibiogram patterns of pyogenic bacteria isolated from pus specimens at tertiary care hospital, Islamabad
Bacteriological profile and Antibiogram patterns
Keywords:
pyogenic infection, antimicrobial resistance, morbidity antibiotic susceptibility pattern, Kirby bauer methodAbstract
Pyogenic wound infections are a significant source of morbidity, because of the development of different resistant strains. To identify the suitable antibiotics for the patient's treatment, it is crucial to understand the sensitivity pattern of antibiotics against the bacterial isolates from clinical pus samples. Antibiotic resistance among various bacteria develops and spreads due to of the careless use of antibiotics in the treatment of diseases. Using the pus samples obtained from different patients from tertiary care Hospital suffering from infections resulting pus formation, the bacteriological profiling and drug susceptibility trends of microbial isolates were studied. The study was executed from August 2022 to January 2023 in the Microbiology Lab of a tertiary care hospital, Islamabad. During the study period, 373 pus samples were acquired from various departments and processed by standard microbiological techniques for identification of bacterial isolates by culturing them on selective and differential media and later antimicrobial susceptibility profile was determined as per Clinical and Laboratory Standard Institute guidelines by using Kirby-Bauer method. Staphylococcus aureus (55.5%) was most prevalent followed by Pseudomonas aeruginosa (23.2%), E.coli (7%), Klebsiella pneumonia (6.2%), Proteus mirabilis (3.54%), Enterococcus (1.96%), Provindicia stuarti (1.8%), Acinetobacter baumannii (0.39%), and Stenotrophomonas maltophilia (0.38%). The most susceptible antibiotics for gram positive isolates were linezolid, vancomycin, rifampicin, and minocycline, whereas for gram negative isolates were cefatrizine and piperacillin+tazobactam. Antibiotic rotation and routine AMR monitoring are advised to stop the spread of resistance.
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Copyright (c) 2024 Bushra Uzair, Bushra Uzair, Zainab Jamal, Maryam Faheem, Itrat Noor
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