Abstract
The main prospective of this study to detect the frequency of different microorganisms isolated from Diabetic Foot Ulcer (DFUs) and also their antibiotic susceptibility pattern. On the basis of purposive sampling technique the medical record of 356 patients was collected who have Diabetic foot ulcer and visited the Sakina Begum Institute of Diabetes and Endocrine Research Lahore (SIDER) from May 2021 to May 2022. Only those samples were included in this study whose bacterial growth was identified through microbiological media and further antimicrobial sensitivity was confirmed by disc diffusion method. About 54.5% of diabetic foot ulcer patients were tested positive for infections by microbes; among which 62% samples had single organism growth and 37% had polymicrobial growth. 34% of the isolated microbes were gram positive while 66% were gram negative. Staphylococcus aureus was the most prevalent isolated organism because it showed the strong resistant pattern against cefotaxime, cefuroxime and ampicillin but vancomycin have the 58% sensitivity for gram positive bacteria. Most of the isolates showed resistance to common antibiotics, so appropriate antibiotic administration is necessary to reduce the resistance pattern in DFUs and needs to be timely treated to avoid from further infection.
Keywords: Diabetes, Foot ulcer, Infections, Micro-organisms, Sensitivity, Antibiotics