Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Hospital Environment

Authors

  • Munzer Ullah University of Okara
  • Hayat Ullah Ullah University of Okara
  • Khaliq Noor Quaid-i-Azam University, Islamabad
  • Maliha Sarfraz The Women University, Multan
  • Misbah Ullah Khan
  • Uzma Bibi Department of Chemistry, University of Okara, Okara-56300, Punjab, Pakistan
  • Ghulam Nabi Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt
  • Maheen Kanwal University of Okara
  • Kainat Ramzan University of Okara
  • Ahmed M. Metwaly Al-Azhar University, Cairo, Egypt

Keywords:

Antibiotics, Pseudomonas aeruginosa, antibiotics, Biofilm, Peliclle.

Abstract

Pseudomonas aeruginosa is a leading cause of disease and death particularly in cystic fibrosis patients and also considered resistance to chemotherapeutic agents. Therefore, it is very difficult to remove the Pseudomonas aeruginosa from the hospital environment by using simple techniques. In the contemporary study, biofilm mediated mechanism of various antimicrobial responses were analyzed. For this purpose, different Pseudomonas aeruginosa clinical isolates were collected from Pakistan medical institute Islamabad (PIMS) hospital and were investigated for pellicle formation. Pseudomonas aeruginosa isolates were studied for different groups of antibiotics including imipenem, meropenem, ceftazidime, amikacin, tobramycin, gentamicin, piperacillin, cefoperazone, and cefotaxime. The goal was to check antimicrobial susceptibility of pseudomonas aeruginosa which shows resistant to tobramycin, imipenem, meropenem, amikacin, gentamicin, cefotaxime, piperacillin, ceftazidime, cefoperazone. Additionally, in this study, Pseudomonas aeruginosa strains were also investigated for pellicle formation. In conclusion, this research work wills highlights the useful mechanism of antibiotics resistance to Pseudomonas aeruginosa infections in clinical practice.

Published

2021-09-11

How to Cite

Munzer Ullah, Ullah, H. U., Khaliq Noor, Maliha Sarfraz, Misbah Ullah Khan, Bibi, U., Ghulam Nabi, Maheen Kanwal, Kainat Ramzan, & Ahmed M. Metwaly. (2021). Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Hospital Environment. Abasyn Journal of Life Sciences, 4(Issue 1), 40-50. Retrieved from http://ajlifesciences.com/ojs/index.php/ajls/article/view/162

Issue

Section

Full Length Research Article